Therefore, not use this product to treat in children younger than 6 years unless specifically directed by the doctor. Limited experience indicates that phenothiazines are not dialyzable. Following the recommendations below, you can prevent your veins from getting dilated further, and your hemorrhoids from becoming larger and protruding even more. In most cases that's enough to stop pain, inflammation, bleeding, or prolapse, and keep it that way for as long as you guard your anus with the same vigilance you guard your credit rating. altace with twins altace
The dosage is based on your age, medical condition, and response to therapy. To lessen stomach upset, take this medicine with meals or immediately after meals, unless otherwise directed by your doctor. Children may be especially sensitive to the effects of antidyskinetics. This may increase the chance of side effects during treatment. The dosage is based on your age, medical condition and response to therapy. Seek emergency medical attention. albendazole contrareembolso
What are the possible side effects of trihexyphenidyl Artane? As you can see even a smallish Corby pickle is huge relative to the anus size. Do not take this medicine within 1 hour of taking medicine for diarrhea. Taking these medicines too close together will make this medicine less effective. Adjust dosage carefully according to individual requirements and response. These medicines may be prescribed together to prevent or treat side effects from your antipsychotic or phenothiazine medicine. In other situations, the combination may increase the likelihood of medicine side effects.
The total daily intake of trihexyphenidyl is tolerated best if divided into 3 doses and taken at mealtimes. Newton's third law, of course: for every action there is an equal and opposite reaction. Never stop an antidepressant medicine without first talking to a healthcare provider. Stopping an antidepressant medicine suddenly can cause other symptoms. rifampicin
To some degree the function and dysfunction of hemorrhoids is similar to calluses that protect joints from friction damage. And, just as calluses on your palms can bulge, blister, and bleed as the result of too much hard labor, so can hemorrhoids from large stools and straining. No surprise there. When ARTANE trihexyphenidyl is used concomitantly with levodopa, the usual dose of each may need to be reduced. Careful adjustment is necessary, depending on side effects and degree of control. An ARTANE trihexyphenidyl dosage of 3 to 6 mg daily, in divided doses, is usually adequate. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure. Signs and symptoms of overdosage may include, alone or in combination, any of the following: drowsiness, dizziness, faintness, irritability, hyperactivity, agitation, severe headache, hallucinations, trismus, opisthotonus, rigidity, convulsions, and coma; rapid and irregular pulse, hypertension, hypotension, and vascular collapse; precordial pain, respiratory depression and failure, hyperpyrexia, diaphoresis, and cool, clammy skin. Also, certain prescription drugs should be avoided. Potential side effects associated with the use of any atropine-like drugs include constipation, drowsiness, urinary hesitancy or retention, tachycardia, dilation of the pupil, increased intraocular tension, weakness, vomiting, and headache. Trihexyphenidyl may also be used for purposes other than those listed in this medication guide.
If you are using the liquid form, use a medication measuring device to carefully measure the prescribed dose. not use a household spoon. If your liquid form is a suspension, shake the bottle well before each dose. The use of drugs with antiperistaltic activity primarily antidiarrheal and antimuscarinic agents, but also antispasmodic agents such as dicyclomine or oxybutynin at high dosages is contraindicated in patients with diarrhea due to pseudomembranous enterocolitis or enterotoxin-producing bacteria. Usual dosage is 1 mg or 2 mg twice daily. Do not administer at doses of more than 6 mg per day or for longer than 12 weeks. Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. 2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have or have a family history of bipolar illness also called manic-depressive illness or suicidal thoughts or actions. 3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member? Rarely, abnormal drug-seeking behavior addiction is possible with this medication. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased. Children: Use and dose must be determined by your doctor. Take this medication at least 1 hour before antacids containing magnesium, aluminum, or calcium. Allow at least 1-2 hours between doses of trihexyphenidyl and certain drugs for diarrhea adsorbent antidiarrheals such as kaolin, pectin, attapulgite. Take this medication at least 2 hours after ketoconazole. Antacids and some drugs for diarrhea may prevent the full absorption of trihexyphenidyl, and this product may prevent the complete absorption of ketoconazole when these products are taken together. When trihexylphenidyl is used as an adjunct to levodopa, consider reducing levodopa and trihexyphenidyl dosages. Once you factor in people under fifty and the undiagnosed, the actual number is probably even greater. If taken after meals, the thirst sometimes induced can be allayed by mint candies, chewing gum or water. Trihexyphenidyl exerts a direct inhibitory effect upon the parasympathetic nervous system. It also has a relaxing effect on smooth musculature; exerted both directly upon the muscle tissue itself and indirectly through an inhibitory effect upon the parasympathetic nervous system. Its therapeutic properties are similar to those of atropine although undesirable side effects are ordinarily less frequent and severe than with the latter. Concurrent use of alcohol or other CNS depressants with trihexyphenidyl may cause increased sedative effects. Diabetes-related anorectal nerve damage. This condition reduces the sensation of urge, so the person doesn't feel a need to defecate. Since certain phenothiazines have been reported to produce retinopathy, the drug should be discontinued if ophthalmoscopic examination or visual field studies should demonstrate retinal changes. It is sometimes possible to maintain the patient on a reduced Trihexyphenidyl HCl dosage after the reactions have remained under control for several days. Instances have been reported in which these reactions have remained in remission for long periods after Trihexyphenidyl HCl therapy was discontinued. Isolated instances of suppurative parotitis secondary to excessive dryness of the mouth, skin rashes, dilatation of the colon, paralytic ileus, and certain psychiatric manifestations such as delusions and hallucinations, plus one doubtful case of paranoia all of which may occur with any of the atropine-like drugs, have been reported rarely with trihexyphenidyl. naprosyn
Phenelzine sulfate should also not be used in combination with buspirone HCl, since several cases of elevated blood pressure have been reported in patients taking MAO inhibitors who were then given buspirone HCl. At least 14 days should elapse between the discontinuation of Phenelzine sulfate and the institution of another antidepressant or buspirone HCl, or the discontinuation of another MAO inhibitor and the institution of Phenelzine sulfate. An encephalopathic syndrome characterized by weakness, lethargy, fever, tremulousness and confusion, extrapyramidal symptoms, leukocytosis, elevated serum enzymes, BUN and FBS has occurred in a few patients treated with lithium plus an antipsychotic. In some instances, the syndrome was followed by irreversible brain damage. Because of a possible causal relationship between these events and the concomitant administration of lithium and antipsychotics, patients receiving such combined therapy should be monitored closely for early evidence of neurologic toxicity and treatment discontinued promptly if such signs appear. This encephalopathic syndrome may be similar to or the same as neuroleptic malignant syndrome NMS. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. There was considerable variation in risk of suicidality among drugs, but a tendency toward an increase in the younger patients for almost all drugs studied. There were differences in absolute risk of suicidality across the different indications, with the highest incidence in MDD. The risk differences drug vs placebo however, were relatively stable within age strata and across indications. Your child may need extra help and encouragement to prepare for added expectations and responsibilities. Treatment of acute overdose involves symptomatic and supportive therapy. Gastric lavage or other methods to limit absorption should be instituted. A small dose of diazepam or a short-acting barbiturate may be administered if CNS excitation is observed. Phenothiazines are contraindicated because the toxicity may be intensified due to their antimuscarinic action, causing coma. Respiratory support, artificial respiration or vasopressor agents may be necessary. Hyperpyrexia must be reversed, fluid volume replaced and acid-balance maintained. Urinary catheterization may be necessary.
Endocrine disorders such as underactive thyroid or adrenal insufficiency. These conditions adversely affect the function of smooth muscles of the colon and rectum. Tardive dyskinesia may appear in some patients on long-term therapy with antipsychotic drugs or may occur after therapy with these drugs has been discontinued. Antiparkinsonism agents do not alleviate the symptoms of tardive dyskinesia and, in some instances, may aggravate them. However, parkinsonism and tardive dyskinesia often coexist in patients receiving chronic neuroleptic treatment, and anticholinergic therapy with Trihexyphenidyl HCl may relieve some of these parkinsonism symptoms. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Just like all other organs, hemorrhoids develop while still in the womb. They are part and parcel of human anatomy, not a pathology or disease. Their function is to protect cushion the internal structures of the anal canal from the passing stools. They are almost like the bearings on which the stools ride. If a hypertensive crisis occurs, Phenelzine sulfate should be discontinued immediately and therapy to lower blood pressure should be instituted immediately. On the basis of present evidence, phentolamine is recommended. The dosage reported for phentolamine is 5 mg intravenously. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when ARTANE trihexyphenidyl is administered to a nursing woman. As with other anticholinergics, trihexyphenidyl may cause suppression of lactation. This medication may pass into milk. Consult your doctor before -feeding. EPS. Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever, and primary central nervous system CNS pathology. Because phenothiazines may interfere with thermoregulatory mechanisms, use with caution in persons who will be exposed to extreme heat. Since ARTANE trihexyphenidyl has atropine-like properties, patients on long-term treatment should be carefully monitored for untoward reactions. Ataxia, shock-like coma, toxic delirium, manic reaction, convulsions, acute anxiety reaction, precipitation of schizophrenia, transient respiratory and cardiovascular depression following ECT. The strangulation of the prolapsed hemorrhoidal tissue. Very disappointed in it and disappointed. generic drugs nitrofurantoin
Abrupt withdrawal of treatment for parkinsonism may result in acute exacerbation of parkinsonism symptoms; therefore, abrupt withdrawal should be avoided. Specific treatment varies by individual and changes as needed if new issues develop. In general, treatment focuses on ways to maintain or improve a person's quality of life and overall health. Trihexyphenidyl alters unusual nerve impulses and relaxes stiff muscles. If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention. For the management of schizophrenia. V" below the score. Available in bottles of 100, 500, and 1000. Death has been reported following overdosage. Therefore, immediate hospitalization, with continuous patient observation and monitoring throughout this period, is essential. Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and only take the next regularly scheduled dose. Do not take a double dose of this medication. Antidepressants are medicines used to treat depression and other illnesses. It is important to discuss all the risks of treating depression and also the risks of not treating it. Patients and their families or other caregivers should discuss all treatment choices with the healthcare provider, not just the use of antidepressants. What are conjugated billary salts? Available as trihexyphenidyl hydrochloride; dosage expressed in terms of the salt. Dry mouth, blurred vision, dizziness, nausea, nervousness. In serious cases, the spasms can become so intense that your eyelids stay shut for up to several hours. Initially, 1 mg; if extrapyramidal reactions are not controlled within a few hours, progressively increase dosage until control is achieved.
MAO inhibitors inhibit the destruction of serotonin and norepinephrine, which are believed to be released from tissue stores by rauwolfia alkaloids. Accordingly, caution should be exercised when rauwolfia is used concomitantly with an MAO inhibitor, including Phenelzine sulfate. Isolated instances of suppurative parotitis secondary to excessive dryness at the mouth, skin rashes, dilatation of the colon, paralytic ileus, and certain psychiatric manifestations such as delusions and hallucinations, plus one doubtful case of paranoia all of which may occur with any of the atropine-like drugs, have been reported rarely with Trihexyphenidyl hydrochloride. If you miss a dose of this medicine, take it as soon as possible. However, if it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Symptoms may include agitation or jitteriness and sometimes insomnia. These symptoms often disappear spontaneously. At times these symptoms may be similar to the original neurotic or psychotic symptoms. Dosage should not be increased until these side effects have subsided. Moderate. These medicines may cause some risk when taken together. Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and only take the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? Take this by with or without food as directed by your doctor, usually twice a day. Inform your doctor if your condition persists or worsens. It is sometimes possible to maintain the patient on a reduced trihexyphenidyl dosage after the reactions have remained under control for several days. Instances have been reported in which these reactions have remained in remission for long periods after trihexyphenidyl therapy was discontinued. Symptoms of a trihexyphenidyl overdose include large pupils; warm, dry skin; flushed face; fever; dry mouth; fast or irregular heartbeat; anxiety; hallucinations; confusion; agitation; hyperactivity; loss of consciousness; and seizures. What should I avoid while taking Artane trihexyphenidyl? cost of valtrex in us
How should I take Artane trihexyphenidyl? The absence of innervations explains why so many people with a history of straining may not realize that they have irreversible hemorrhoidal disease, until suddenly confronted with hemorrhoidal bleeding or prolapsed hemorrhoids. While it is usually not necessary to exceed dosages of 15 mg daily, some older children with severe symptoms may require higher dosages. Trihexyphenidyl hydrochloride occurs as a white or creamy-white, almost odorless, crystalline powder. It is very slightly soluble in ether and benzene, slightly soluble in water and soluble in methanol. Both and are designed to help relax tense muscles, strengthen muscles, and keep joints flexible. breathing exercises are sometimes used to try to prevent infections. Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Since trihexyphenidyl has atropine-like properties, patients on long-term treatment should be carefully monitored for untoward reactions. If you are experiencing an acute stage of hemorrhoidal disease, follow your doctor's directions until the symptoms subside. Do not drop prescribed medication or recommended laxatives, unless you successfully replace them by the safer means, methods, and approaches recommended on this site. CBC monitored frequently during the first few months of therapy and should discontinue Trifluoperazine Hydrochloride Tablets, USP at the first sign of a decline in WBC in the absence of other causative factors. Minor side effects, such as dryness of the mouth, blurring of vision, dizziness, mild nausea or nervousness, will be experienced by 30 to 50 percent of all patients. These sensations, however, are much less troublesome with Trihexyphenidyl HCl than with belladonna alkaloids and are usually less disturbing than unalleviated parkinsonism. Such reactions tend to become less pronounced, and even to disappear, as treatment continues. Even before these reactions have remitted spontaneously, they may often be controlled by careful adjustment of dosage form, amount of drug, or interval between doses. The bleeding related to ulcers, polyps, and tumors in the colon and the rectum may look identical to hemorrhoids-related bleedings. The appearance of mucus along with the blood is a telltale sign of inflammatory bowel disease or colorectal tumors. So any time you see blood, mucus, or both in the toilet bowl or on the toilet paper, get checked immediately. Initiate with low dosage; titrate dosage gradually. Benztropine mesylate tablet US prescribing information. With prolonged administration at high dosages, the possibility of cumulative effects, with sudden onset of severe central nervous system or vasomotor symptoms, should be kept in mind. Side Effects List Trihexyphenidyl HCL side effects by likelihood and severity.
Chewable forms of this medication should be chewed thoroughly before swallowing. It involves both the muscles around your and your eyelid. Unlike the other two types, it usually affects only one side of the face. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tolterodine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain problems , slow heartbeat, QT prolongation in the family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. If you are taking the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Possible tachycardia; a use with caution and carefully monitor patients with cardiac disease or hypertension. The occurrence of angle-closure glaucoma in patients receiving trihexyphenidyl has been reported blindness has been reported in some cases. Paradoxical sinus bradycardia, dry skin, and cycloplegia have been reported. Dosage should be increased to at least 60 mg per day at a fairly rapid pace consistent with patient tolerance. It may be necessary to increase dosage up to 90 mg per day to obtain sufficient MAO inhibition. Many patients do not show a clinical response until treatment at 60 mg has been continued for at least 4 weeks. HIAA levels, VMA levels possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Sometimes these may be accompanied by involuntary movements of extremities. In rare instances, these involuntary movements of the extremities are the only manifestations of tardive dyskinesia. A variant of tardive dyskinesia, tardive dystonia, has also been described. buspirone
External hemorrhoids cause pain, the sensation of which is related to inflammation of the skin that surrounds the thrombosed venal prolapse. You may not be able to take trihexyphenidyl or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above. ARTANE trihexyphenidyl is contraindicated in patients with hypersensitivity to trihexyphenidyl HCl or to any of the tablet or elixir ingredients. Pruritus, skin rash, sweating. Exhibits atropine-like action and exerts antispasmodic effects on parasympathetic-innervated peripheral structures, including smooth muscle. An uncommon withdrawal syndrome following abrupt withdrawal of Phenelzine sulfate has been infrequently reported. Signs and symptoms of this syndrome generally commence 24 to 72 hours after drug discontinuation and may range from vivid nightmares with agitation to frank psychosis and convulsions. This syndrome generally responds to reinstitution of low-dose Phenelzine sulfate therapy followed by cautious downward titration and discontinuation. If any of these effects persist or worsen, contact your doctor or promptly. V" below the score. Available in bottles of 100, 500 and 1000.
If the stool's appearance is already tar-like, it may mean that there is internal bleeding at some point upstream, beginning from the esophagus. The color changes to tar after coagulated blood mixes with feces. As with other anticholinergics, trihexyphenidyl may cause suppression of lactation. Therefore, trihexyphenidyl should only be used if the expected benefit to the mother outweighs the potential risk to the infant. This information is generalized and not intended as specific medical advice. It is not known whether trihexyphenidyl passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Bleeding specific to hemorrhoidal disease isn't usually from the thrombosed veins another popular misconception but from the abrasions, cuts, fissures, fistulas, or ulcerations of the mucosal membrane that lines the anal canal. Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. To make this point loud and clear, let me remind you again that the most debilitating hemorrhoids-related conditions, such as torture-like pain and the inability to sit or walk, aren't related to internal hemorrhoids, but external. This may interfere with certain laboratory tests including possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. Do not use medications containing dexchlorpheniramine while using chlorpheniramine. The 2 mg tablets are white film-coated, round, unscored tablets debossed with T4 on one side of the tablet and M on the other side. Despite these considerable risks and lethal outcomes, straining isn't only considered normal, but is also encouraged by doctors who advise patients to strengthen their abdominal and pelvic muscles, so they can strain even harder. indian pharmacy zyloprim
Trihexyphenidyl is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used to treat and prevent the same muscular conditions when they are caused by drugs such as chlorpromazine Thorazine fluphenazine Prolixin perphenazine Trilafon haloperidol Haldol thiothixene Navane and others. Anyone considering the use of Phenelzine sulfate in a child or adolescent must balance the potential risks with the clinical need. So if your child has had a faux pas, don't scream at or shame her, otherwise you'll make her too self-conscious, too controlling and, soon, too constipated and prone to straining in order to overcome her "insensitive" anus or overly constrained anal canal. Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. Whether Trihexyphenidyl HCl may best be given before or after meals should be determined by the way the patient reacts. Postencephalitic patients, who are usually more prone to excessive salivation, may prefer to take it after meals and may, in addition, require small amounts of atropine which, under such circumstances, is sometimes an effective adjuvant. If Trihexyphenidyl HCl tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, chewing gum or water. Because of increased sedative effects, patients should be cautioned to avoid the use of alcohol or other CNS depressants while taking trihexyphenidyl. Dizziness, lightheadedness, or fainting may occur, especially when you get up from lying or sitting. Getting up slowly may help. If the problem continues or gets worse, check with your doctor. Trihexyphenidyl may be substituted, in whole or in part, for other parasympathetic inhibitors. The usual technique is partial substitution initially, with progressive reduction in the other medication as the dose of trihexyphenidyl is increased. These kind of picture-perfect, finger-sized, soft and moist stools require no more effort to pass out than urination. In other words, normal defecation is a practically unnoticeable act, just like it was when you were a healthy child. ARTANE trihexyphenidyl may be substituted, in whole or in part, for other parasympathetic inhibitors. The usual technique is partial substitution initially, with reduction in the other medication as the dose of trihexyphenidyl HCl is increased. Healthy bacteria reside and procreate inside the protective layer of the mucosal membrane, and derive their nutrients from mucus. To give them a good home and head start, your mucosal membrane must be healthy, well-nourished, and populated with beneficial bacteria. To accomplish this goal, follow my recommendations in the guide.
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What happens if I miss a dose Artane? The actual release of salts may be sudden, without any apparent reason, or preceded by a specific event, such as an airplane flight, certain foods, or medication. Apparently, the changes in atmospheric pressure or some other factors may cause the release of billiary salts during or after the flight. As with all antipsychotic agents, tardive dyskinesia may appear in some patients on long-term therapy or may appear after drug therapy has been discontinued. The syndrome can also develop, although much less frequently, after relatively brief treatment periods at low doses. This syndrome appears in all age groups. Although its prevalence appears to be highest among elderly patients, especially elderly women, it is impossible to rely upon prevalence estimates to predict at the inception of antipsychotic treatment which patients are likely to develop the syndrome. The symptoms are persistent and in some patients appear to be irreversible. buy unisom berlin unisom
Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. Other therapies may also be needed, depending on specific needs. This particular mechanism is behind the action of the rectal enemas, glycerin suppositories, and most laxatives. The number of capsules, tablets, or teaspoonfuls of elixir that you take depends on the strength of the medicine.
Check the labels on all your medicines such as or -and-cold products because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Jaundice of the cholestatic type of hepatitis or liver damage has been reported. If fever with grippe-like symptoms occurs, appropriate liver studies should be conducted. If tests indicate an abnormality, stop treatment. There are no data on the lethal dose in man. The pathophysiologic effects of massive overdosage may persist for several days, since the drug acts by inhibiting physiologic enzyme systems. With symptomatic and supportive measures, recovery from mild overdosage may be expected within 3 to 4 days. lechak.info famciclovir
Symptoms may include: mask-like facies; drooling; tremors; pill-rolling motion; cogwheel rigidity; and shuffling gait. Reassurance and sedation are important. In most cases these symptoms are readily controlled when an antiparkinsonism agent is administered concomitantly. Antiparkinsonism agents should be used only when required. Generally, therapy of a few weeks to 2 or 3 months will suffice. After this time, patients should be evaluated to determine their need for continued treatment. Note: Levodopa has not been found effective in pseudoparkinsonism. Antiparkinsonism agents do not alleviate the symptoms of tardive dyskinesia, and in some instances may aggravate them. However, and tardive dyskinesia often coexist in patients receiving chronic neuroleptic treatment, and anticholinergic therapy with ARTANE trihexyphenidyl may relieve some of these parkinsonism symptoms. ARTANE trihexyphenidyl is not recommended for use in patients with tardive dyskinesia unless they have concomitant Parkinson's disease.